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Inexperienced-lipped mussel & osteoarthritis remedy: How considered one of nature’s strongest anti-inflammatories works
Are you involved about your canine’s mobility and joint well being? Dive into this weblog to get a greater understanding of the well being advantages of green-lipped mussel for canines and the way it might help relieve the signs of osteoarthritis and scale back using anti-inflammatory medicine.
Mobility is the important thing factor in conserving our canine associates wholesome and completely happy for a few years to return. Pondering again to my first canine, Skai, I used to be so grateful he was in a position to go climbing with us within the mountains even on the age of 15.
However whereas he appeared unstoppable, ultimately stiffness and aches began to set in. Seeing your canine decelerate is hard for any pet mother or father as mobility is all the things for them — it is pleasure, freedom, and life itself.
Happily, there are pure methods to assist your canine’s mobility and improve their lifespan, considered one of them being the Perna mussel or green-lipped mussel.
In 2009, a examine referred to as An evidence-based systematic review of green-lipped mussel (Perna canaliculus)(1) confirmed that New Zealand green-lipped mussel gives a clinically vital optimistic remedy impact on osteoarthritis (joint irritation).
This examine included a assessment of 9 scientific trials, specializing in the consequences of green-lipped mussels on OA ache and mobility, however additionally confirmed that green-lipped mussels improved gastrointestinal signs in OA sufferers taking non-steroidal anti-inflammatory medicines (NSAIDs) which are extensively utilized in human and veterinary medication. These medicine are identified to trigger gastrointestinal, kidney, and liver side effects, leading to a deeper imbalance within the physique.
However that is not all, what makes green-lipped mussels so useful for canines and other people lies within the highly effective vitamins it accommodates.
What makes green-lipped mussels so distinctive?
A latest examine performed by a Japanese analysis workforce centered on the compounds behind the green-lipped mussel’s optimistic results on joint well being, ache administration, and mobility — the bioactive glycosaminoglycans (GAGs)(2).
Marine invertebrates akin to mussels are a wealthy supply of those extremely sulfated and uncommon glycosaminoglycans. Perna canaliculus is among the greatest sources produced on a big scale in New Zealand.
The glycosaminoglycans from the green-lipped mussel, primarily chondroitin sulfate (CS) and heparan sulfate (HS), exhibit a number of notable organic results:
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Encouraging nerve progress: Sure chondroitin sulfate chains, particularly these with a particular kind of sugar pairing (GlcA-GalNAc(4,6-O-disulfate)), have been discovered to assist in the creation of connections between nerve cells. This discovery hints at attainable makes use of within the fields of neurology and regenerative medication, the place selling nerve progress and restore is required.
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Joint well being and osteoarthritis remedy: Chondroitin sulfate is usually used for its potential advantages in joint well being, significantly within the remedy of osteoarthritis. It’s believed to contribute to the upkeep and restore of cartilage, the connective tissue that traces and cushions joints.
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Anti-inflammatory properties: Each chondroitin sulfate and heparan sulfate possess anti-inflammatory properties, that are useful in decreasing irritation in instances of arthritis.
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Tissue homeostasis (stability) and cell proliferation (creation and progress): GAGs play important roles in mobile phenomena like cell proliferation, cell adhesion, differentiation, and tissue homeostasis.
One other examine, this time analysing the effects of a diet enriched with green-lipped mussel in dogs with osteoarthritis, noticed that there was a big improve in Omega-3 fatty acids ranges of their blood after 60 days. The house owners additionally reported enhancements of their canines’ ache and exercise ranges after switching to this weight loss plan.
Why I selected so as to add green-lipped mussel to JointButter
For these of you who’ve missed the newest information, JointButter, our new product and the world’s first fermented joint and mobility assist complement for canines, can be quickly added to our product line up.
I’ve researched numerous vitamins, herbs, and superfoods for a few years as a way to provide you with the very best system that will make a transparent distinction for our canines’ joint well being and mobility.
That is how I got here throughout the green-lipped mussel and its highly effective anti-inflammatory and joint-repair properties. The glycosaminoglycans (GAGs) from Perna mussels have a singular construction and bioactivity, making it a well-liked ingredient in canine and human mobility formulation.
Whereas I’ve additionally added chondroitin sulfate and glucosamine to JointButter, the addition of a whole-food supply of GAGs from Perna mussels considerably boosts the efficiency of the complement and will increase the spectrum of obtainable glycosaminoglycans.
How are green-lipped mussels raised and harvested?
Produced solely in New Zealand, green-lipped mussel manufacturing entails a number of steps.
Seeds are first collected and planted in a hatchery. As soon as they hatch into larvae, they connect themselves to rocks, lengthy ropes, and different laborious surfaces.
As soon as connected, a metamorphosis into juvenile and consecutively into grownup mussels follows. Inexperienced-lipped mussels are able to be harvested in 26 to 48 months.
A word on the sustainability of green-lipped mussel manufacturing
When formulating JointButter, my workforce and I didn’t simply deal with the standard and science-backed efficacy of the substances we chosen; we additionally paid shut consideration to their environmental sustainability.
The areas the place Perna mussels are harvested are underneath the stewardship of the producers in a profitable collaboration with Mussel Reef Restoration Belief and Revive Our Gulf Foundation.
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Inexperienced-lipped mussel for canines FAQ
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Are green-lipped mussels good for canines?
Sure, green-lipped mussels or Perna mussels include glycosaminoglycans, akin to glucosamine and chondroitin that assist scale back irritation within the physique, restore and shield the cartilage, and promote optimum joint well being in canines.
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What are the unintended effects of inexperienced lipped mussel?
There aren’t any identified unintended effects to supplementing your canine’s or pet’s weight loss plan with green-lipped mussels. Nonetheless, if your canine has an allergy to shellfish, it is best to attempt this ingredient in small quantities when beginning this complement.
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Is inexperienced lipped mussel higher than glucosamine for canines?
Inexperienced-lipped mussels naturally include a robust mixture of anti-inflammatory and joint-protective vitamins, together with glycosaminoglycans, chondroitin and glucosamine, which helps cartilage restore and joint mobility.
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Is inexperienced lipped mussel higher than fish oil?
Fish oil will not be thought of to be the identical as Perna Mussel because of totally different nutrient profile. As well as, fish oil is usually unsustainable possibility because of overfishing. Heavy-metal focus also needs to be a concern if you wish to shield your canine’s well being.
- Is Inexperienced Lipped Mussel Harvest sustainable?
Inexperienced-lipped mussel dietary supplements are thought of safer for the planet and your canine companion as their harvesting is overseen by the Mussel Reef Restoration Belief in New Zealand.
Article references:
1. ”Inexperienced-lipped mussel assessment” by Catherine Ulbricht and workforce. PMID: 22435354 DOI: 10.1080/19390210802690191
2. “Bioactive glycosaminoglycans examine” in Biochemical and Biophysical Analysis Communications, Quantity 612, 5 July 2022, Pages 50-56; Ayumu Mubuchi and workforce.
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